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International guidelines for the use of the treatment lack clarity regarding the recommended type of corticosteroid and the gestational window of treatment administration, while the National Institutes of Health (NIH) does not currently recommend corticosteroid therapy in preterm infants; the European Medicines Agency (EMA) only recommends the use of selective beta 2 agonists up to 22 weeks of gestation. 8,9 In contrast, most other US agencies recommend corticosteroid therapy during the last week of gestation, d ball pills. 10 As an obstetrician, I am aware of the importance of maternal and neonatal survival and the potential importance of treatment with corticosteroids and other medications during pregnancy. However, I am equally aware of the relative risks and uncertainty regarding the use of the medication in preterm infants. A study in 2002 of women with neonatal hyperthyroidism found that the percentage of preterm born with severe hypothyroidism varied by gestational age; the highest rate occurred in 35-36 weeks gestation (>20% of the gestational age range), followed by 30-31 weeks (16%) and 23-24 weeks (10%).
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